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Table of Contents | Genet. Mol. Res. 10 (3)


Combining ability of tropical maize lines for seed quality and agronomic traits

Genet. Mol. Res. 10 (3) : 2268 - 2278
Abstract:

Studies of genetic effects of early selection of maize based on seed quality traits are rare, especially those that use materials from different heterotic groups. These studies are also useful in tropical environments and for the advancement of sustainable agriculture with...

Zea mays L., Genetic effects, Seed quality tests, Grain yield, Early selection, Hybrids
Abstract | Full Text PDF

Gene expression in swine granulosa cells and ovarian tissue during the estrous cycle

Genet. Mol. Res. 10 (3) : 2258 - 2267
Abstract:

The components of the insulin-like growth factor (IGF) system appear to be involved in regulation of ovarian follicular growth and atresia in the pig. We investigated the expression pattern of mRNAs for IGF1 (IGF1), its binding proteins (IGFBP1, ...

Follicular development, Growth factors, RT-PCR
Abstract | Full Text PDF

Retraction

RETRACTION of “Genetic and biochemical analyses of sensor kinase A in Bacillus subtilis sporulation” by J.C. Nguele, P. Eswaramoorthy, M. Bhattacharya, E. Ngou-Milama and M. Fujita. Genet. Mol. Res. 9 (1): 573-590 (2010)

Genet. Mol. Res. 10 (3) : 2257 - 2257
Abstract:

This paper has been retracted (without the consent of the submitting author, Jean- Calvin Nguele) because of serious fraud and plagiary issues. The submission letter, sent by Jean-Calvin Nguele, included forged signatures of Prahathees Eswaramoorthy, Mou Bhattacharya, and...

Abstract | Full Text PDF

Isolation and characterization of 16 novel microsatellite loci in two inbred strains of the Chinese hamster (Cricetulus griseus)

Genet. Mol. Res. 10 (3) : 2245 - 2256
Abstract:

The Shanyi inbred A and E strains of the Chinese hamster are widely used in biomedical research, but detailed genetic characterization has been lacking. We developed microsatellite markers that could be used for genetic diversity analysis and linkage map construction. We...

Chinese hamster, Enriched library, Microsatellite marker, Genetic differentiation
Abstract | Full Text PDF

Modeling of crossbred cattle growth, comparison between cubic and piecewise random regression models

Genet. Mol. Res. 10 (3) : 2230 - 2244
Abstract:

Two analyses, cubic and piecewise random regression, were conducted to model growth of crossbred cattle from birth to about two years of age, investigating the ability of a piecewise procedure to fit growth traits without the complications of the cubic model. During a four-...

Crossbred cattle, Growth, Cubic, Random regression, Piecewise
Abstract | Full Text PDF

Short Communication

Isolation and characterization of microsatellite markers for the White Cloud Mountain minnow (Tanichthys albonubes) in wild and cultured populations

Genet. Mol. Res. 10 (3) : 2223 - 2229
Abstract:

We developed 12 microsatellite loci for the endangered minnow species, Tanichthys albonubes, using PCR-based isolation of microsatellite arrays. These new markers were tested in 26 individuals from a wild population collected from Guangzhou in China and 26...

Tanichthys albonubes, Microsatellite marker, bottleneck, Endangered species
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Lack of an association between a single nucleotide polymorphism in the bovine myogenic determination 1 (MyoD1) gene and meat quality traits in indigenous Chinese cattle breeds

Genet. Mol. Res. 10 (3) : 2213 - 2222
Abstract:

The myogenic determination 1 (MyoD1) gene is a member of the MyoD gene family. It encodes for skeletal muscle-specific transcription factors containing highly conserved basic helix-loop-helix regions that perform important roles in the initiation, maintenance, and...

Allelic frequencies, Myogenic determination gene 1, meat quality, Single nucleotide polymorphism, Qinchuan cattle
Abstract | Full Text PDF

Association of eNOS gene polymorphisms with essential hypertension in the Han population in southwestern China

Genet. Mol. Res. 10 (3) : 2202 - 2212
Abstract:

Endothelial nitric oxide synthase (eNOS) plays an important role in maintaining blood pressure homeostasis and vascular integrity. Polymorphisms in the eNOS gene have been found to be associated with hypertension in different human populations, including Northern...

Essential hypertension, eNOS, SNPs, Han population, Haplotype
Abstract | Full Text PDF

Effect of pregnancy on the genetic evaluation of dairy cattle

Genet. Mol. Res. 10 (3) : 2190 - 2201
Abstract:

We investigated the effect of stage of pregnancy on estimates of breeding values for milk yield and milk persistency in Gyr and Holstein dairy cattle in Brazil. Test-day milk yield records were analyzed using random regression models with or without the effect of pregnancy...

Days open, Lactation curves, Random regression model, Stage of pregnancy
Abstract | Full Text PDF

Improved thermostable α-amylase activity of Bacillus amyloliquefaciens by low-energy ion implantation

Genet. Mol. Res. 10 (3) : 2181 - 2189
Abstract:

Thermostable α-amylase is of great importance in the starch fermentation industry; it is extensively used in the manufacture of beverages, baby foods, medicines, and pharmaceuticals. Bacillus amyloliquefaciens produces thermostable α-amylase; however,...

Ion implantation, Bacillus amyloliquefaciens, Thermostable α-amylase
Abstract | Full Text PDF

Genetic diversity of Annona crassiflora (Annonaceae) in northern Minas Gerais State

Genet. Mol. Res. 10 (3) : 2172 - 2180
Abstract:

Genetic diversity analyses of tropical tree species are relevant to landscape management, plant genetic resource inventory, and biological conservation of threatened species. Annona crassiflora is an endangered fruit tree native to the Cerrado biome that is...

Annona crassiflora, Northern of Minas Gerais, Genetic diversity
Abstract | Full Text PDF

Expression of aquaporin-4 in human supratentorial meningiomas with peritumoral brain edema and correlation of VEGF with edema formation

Genet. Mol. Res. 10 (3) : 2165 - 2171
Abstract:

Peritumoral brain edema is a common complication of meningiomas. It is believed that vascular endothelial growth factor (VEGF), as an angiogenic factor, plays a vital role in edema formation. Aquaporin-4 (AQP4) is a small integral membrane protein that regulates water in...

meningiomas, Peritumoral brain edema, Aquaporin-4, Vascular endothelial growth factor
Abstract | Full Text PDF

MtDNA variability in whitefly (Bemisia tabaci) populations in Brazil

Genet. Mol. Res. 10 (3) : 2155 - 2164
Abstract:

Bemisia tabaci (Hemiptera: Aleyrodidae) consists of a complex of morphologically indistinct biotypes that vary mainly in their capacity to transmit plant viruses and to induce physiological disorders in plants of economic importance. The adaptability of B. tabaci ...

Insecta, Aleyrodidae, Whitefly, Genetic diversity, Molecular characterization
Abstract | Full Text PDF

Case Report

Molecular characterization of microduplication 22q11.2 in a girl with hypernasal speech

Genet. Mol. Res. 10 (3) : 2148 - 2154
Abstract:

We present a 12-year-old girl with karyotype 46,XX. A comparative genomic hybridization array revealed a 3.172-Mb microduplication on 22q11.2. This chromosome 22q11.2 region microduplication has been described in patients with variable phenotypes; a large majority of them...

Array-CGH, Hypernasal speech, Temporal hair loss, Microduplication 22q11.2, Mental retardation
Abstract | Full Text PDF

Association between IGF2 and CYP21 gene polymorphisms and characteristics of economic interest in Nellore cattle

Genet. Mol. Res. 10 (3) : 2140 - 2147
Abstract:

We analyzed two single nucleotide polymorphisms (SNPs) of the IGF2 and CYP21 genes in Nellore cattle participating in the Brazilian Animal Breeding Program. The SNPs were found in exon 6 of the IGF2 (insulin-like growth factor 2) gene (RFLP/...

Genotype-phenotype association, SNPs, IGF2, CYP21, Cattle
Abstract | Full Text PDF

Inheritance of kernel row number, a multicategorical threshold trait of maize ears

Genet. Mol. Res. 10 (3) : 2133 - 2139
Abstract:

Information about the inheritance of threshold traits is scarce, especially in plants. We examined the genetic control of kernel row number in maize (Zea mays). Knowledge of this inheritance is especially important because it is a primary component of grain yield...

Crop improvement, Threshold traits, Kernel row number
Abstract | Full Text PDF

A transient assay for recombination demonstrates that Arabidopsis SNM1 and XRCC3 enhance non-homologous recombination

Genet. Mol. Res. 10 (3) : 2104 - 2132
Abstract:

Replacement of endogenous genes by homologous recombination is rare in plants; the majority of genetic modifications are the result of transforming DNA molecules undergoing random genomic insertion by way of non-homologous recombination. Factors that affect chromatin...

Extra-chromosomal recombination, Agro-infiltration, Non-homologous recombination, Homologous recombination, Plant genetic modification, Transient Dual-Luciferase® assays
Abstract | Full Text PDF

Gene expression analysis of demineralized bone matrix-induced osteogenesis in human periosteal cells using cDNA array technology

Genet. Mol. Res. 10 (3) : 2093 - 2103
Abstract:

Demineralized bone matrix (DBM) has been widely investigated as a biomaterial to promote new bone formation and is utilized clinically for bone repair and regeneration. We investigated gene expression patterns of osteogenic differentiation in human periosteal (HPO) cells...

cDNA array, Demineralized bone matrix, Osteogenesis, Gene expression, Human periosteal cells
Abstract | Full Text PDF

Morphometric and molecular analysis of mackerel (Rastrelliger spp) from the west coast of Peninsular Malaysia

Genet. Mol. Res. 10 (3) : 2078 - 2092
Abstract:

Mackerel (Scombridae; Rastrelliger) are small commercially important pelagic fish found in tropical regions. They serve as a cheap source of animal protein and are commonly used as live bait. By using a truss morphometrics protocol and RAPD analysis, we examined...

Genetic variation, RAPD, Multivariate analysis, Morphometric, Rastrelliger spp
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A novel SNP of the C/EBPα gene associated with superior meat quality in indigenous Chinese cattle

Genet. Mol. Res. 10 (3) : 2069 - 2077
Abstract:

CCAAT/enhancer-binding protein alpha (C/EBPa) is an essential transcriptional factor regulating the differentiation of adipocytes. We report a novel single nucleotide polymorphism (C271A) of the C/EBPa gene in six indigenous Chinese cattle breeds using PCR-SSCP and DNA...

Bovine C/EBPa gene, Genetic polymorphism, PCR-SSCP, Meat quality traits
Abstract | Full Text PDF

Short Communication

Isolation and characterization of microsatellite markers for the Korean rockfish, Sebastes schlegeli

Genet. Mol. Res. 10 (3) : 2065 - 2068
Abstract:

The Korean rockfish (Sebastes schlegeli) is an important commercial fish that is widely used in aquaculture. We isolated and characterized 18 polymorphic microsatellite loci from the Korean rockfish using a (GT)13-enriched genomic library. Polymorphism...

Korean rockfish, Sebastes schlegeli, Genetic structure, Microsatellite loci
Abstract | Full Text PDF

Single nucleotide polymorphisms in CAPN and leptin genes associated with meat color and tenderness in Nellore cattle

Genet. Mol. Res. 10 (3) : 2057 - 2064
Abstract:

We analyzed single nucleotide polymorphisms in calpain, leptin, leptin receptor, and growth hormone receptor genes and their association with color, drip and cooking losses of longissimus muscle at 7, 14 and 21 days postmortem in 638 purebred Nellore bulls slaughtered...

Beef, Bovine, Genome, Livestock, Molecular markers, SNP
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Comparative genetic analysis of trichome-less and normal pod genotypes of Mucuna pruriens (Fabaceae)

Genet. Mol. Res. 10 (3) : 2049 - 2056
Abstract:

Velvet bean (Mucuna pruriens) seeds contain the catecholic amino acid L-DoPA (L-3,4-dihydroxyphenylalanine), which is a neurotransmitter precursor and used for the treatment of Parkinson’s disease and mental disorders. The great demand for L-DoPA is largely...

Mucuna pruriens, Velvet bean, L-DoPA, RAPD profiling, Genetic divergence, Molecular polymorphism
Abstract | Full Text PDF

Response to treatment with imatinib mesylate in previously treated chronic-phase chronic myeloid leukemia patients in a hospital in Brazil

Genet. Mol. Res. 10 (3) : 2038 - 2048
Abstract:

We analyzed the results of treatment with imatinib mesylate in 70 patients with chronic-phase chronic myeloid leukemia who had previously been treated (with second-line or higher imatinib), many of them in a late chronic phase. The median follow-up period was 60.5 months (...

Chronic myeloid leukemia, Imatinib mesylate, Cytogenetic response
Abstract | Full Text PDF

Short Communication

Isolation and characterization of tetranucleotide repeat polymorphic microsatellite loci in Larus saundersi (Aves, Laridae)

Genet. Mol. Res. 10 (3) : 2034 - 2037
Abstract:

Nine polymorphic microsatellite loci were isolated, using tetranucleotide repeat oligonucleotide probes from an enriched DNA library of the globally “vulnerable” Saunders’s gull (Larus saundersi), collected from the Yancheng coastal wetland, one...

Saunders’s gull, Larus saundersi, Microsatellite, Genetic marker, Polymorphism
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Characterization of chloroplast DNA microsatellites from Saccharum spp and related species

Genet. Mol. Res. 10 (3) : 2024 - 2033
Abstract:

Microsatellites, or simple sequence repeats (SSRs), and their flanking regions in chloroplast genomes (plastomes) of some species of the family Poaceae were analyzed in silico to look for DNA sequence variations. Comparison of the complete chloroplast DNA...

cpSSR, Plastome, Nucleotide polymorphism, Phylogeny, Molecular markers
Abstract | Full Text PDF

Effects of intra- and extracellular factors on anti-aging klotho gene expression

Genet. Mol. Res. 10 (3) : 2009 - 2023
Abstract:

Inactivation of the klotho gene in mice causes serious systemic disorders, resembling human aging. However, at the molecular level, its action mechanisms are not well understood. The stimulatory or inhibitory effects of cis- and trans-regulatory factors on the...

klotho gene, Anti-aging, Apoptosis, PTH, IGF-1, Angiotensin-II
Abstract | Full Text PDF

Association of serum sex steroid levels and bone mineral density with CYP17 and CYP19 gene polymorphisms in postmenopausal women in Turkey

Genet. Mol. Res. 10 (3) : 1999 - 2008
Abstract:

Many clinical conditions, including osteoporosis, are associated with serum levels of sex steroids. Enzymes that regulate rate-limiting steps of steroidogenic pathways, such as CYP17 and CYP19, are also regarded as significant factors that may cause the development of these...

BMD, CYP17, CYP19, Estradiol, Osteoporosis, Polymorphism
Abstract | Full Text PDF

Novel representation of RNA secondary structure used to improve prediction algorithms

Genet. Mol. Res. 10 (3) : 1986 - 1998
Abstract:

We propose a novel representation of RNA secondary structure for a quick comparison of different structures. Secondary structure was viewed as a set of stems and each stem was represented by two values according to its position. Using this representation, we improved the...

RNA secondary structure, Dot plots, Stem, Comparative sequence analysis
Abstract | Full Text PDF

Apolipoprotein E polymorphism in elderly Japanese-Brazilian immigrants does not explain the reduced cardiovascular risk factor incidence

Genet. Mol. Res. 10 (3) : 1975 - 1985
Abstract:

Study of immigrant populations may contribute to a better understanding of the epidemiology of diseases associated with the aging process. We examined the prevalence of cardiovascular risk factors, including apolipoprotein E (ApoE) polymorphism, in elderly subjects who were...

Cardiovascular risk, Apolipoprotein E, Longevity, Brazilian-Japanese elderly, Aging, Obesity
Abstract | Full Text PDF