Research Article

Back fat thickness and meat tenderness are associated with a 526 T→A mutation in the exon 1 promoter region of the MyF-5 gene in Chinese Bos taurus

Published: December 12, 2011
Genet. Mol. Res. 10 (4) : 3070-3079 DOI: https://doi.org/10.4238/2011.December.12.6
Cite this Article:
(2011). Back fat thickness and meat tenderness are associated with a 526 T→A mutation in the exon 1 promoter region of the MyF-5 gene in Chinese Bos taurus. Genet. Mol. Res. 10(4): gmr1358. https://doi.org/10.4238/2011.December.12.6
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Abstract

Qualitative trait loci (QTL) for growth and meat quality traits in cattle (Bos taurus) have been previously mapped to three chromosome regions, 0 to 30, 55 to 70, and 70 to 80 cM on chromosome 5. We evaluated the allele frequencies and gene-specific single nucleotide polymorphisms (SNPs) of bovine myogenic factor 5 (MyF-5) in the QTL regions and their associations with live weight and meat characteristics in indigenous Chinese cattle breeds. PCR-SSCP methodology showed a T>A mutation at 526 bp. Least square analysis revealed a significant association of this SNP with backfat thickness and meat tenderness (P 0.05). The genotypic frequencies among all five cattle breeds showed moderate diversity (0.25 Bos taurus. This SNP could be useful for marker-assisted selection for meat quality traits in these cattle.

Qualitative trait loci (QTL) for growth and meat quality traits in cattle (Bos taurus) have been previously mapped to three chromosome regions, 0 to 30, 55 to 70, and 70 to 80 cM on chromosome 5. We evaluated the allele frequencies and gene-specific single nucleotide polymorphisms (SNPs) of bovine myogenic factor 5 (MyF-5) in the QTL regions and their associations with live weight and meat characteristics in indigenous Chinese cattle breeds. PCR-SSCP methodology showed a T>A mutation at 526 bp. Least square analysis revealed a significant association of this SNP with backfat thickness and meat tenderness (P 0.05). The genotypic frequencies among all five cattle breeds showed moderate diversity (0.25 Bos taurus. This SNP could be useful for marker-assisted selection for meat quality traits in these cattle.