Research Article

Regulation network analysis of testicular seminoma at various stages of progression

Published: March 11, 2013
Genet. Mol. Res. 12 (4) : 4297-4307 DOI: https://doi.org/10.4238/2013.March.11.11
Cite this Article:
(2013). Regulation network analysis of testicular seminoma at various stages of progression. Genet. Mol. Res. 12(4): gmr2369. https://doi.org/10.4238/2013.March.11.11
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Abstract

Testicular seminoma has become the most common solid malignancy in young men, especially in the 20s group. We obtained the gene expression profile of human testicular seminoma cells from NCBI, identified the differentially expressed genes of testicular seminoma cells of different stages, and constructed the regulation networks of different stages of testicular seminoma using bioinformatics methodology. Forty differentially expressed genes of testicular seminoma cells of different stages were identified. These genes and pathways are apparently involved in the progression of testicular seminoma.

Testicular seminoma has become the most common solid malignancy in young men, especially in the 20s group. We obtained the gene expression profile of human testicular seminoma cells from NCBI, identified the differentially expressed genes of testicular seminoma cells of different stages, and constructed the regulation networks of different stages of testicular seminoma using bioinformatics methodology. Forty differentially expressed genes of testicular seminoma cells of different stages were identified. These genes and pathways are apparently involved in the progression of testicular seminoma.