Research Article

Clinical significance of CD44 expression in children with hepatoblastoma

Published: October 27, 2015
Genet. Mol. Res. 14 (4) : 13203-13207 DOI: https://doi.org/10.4238/2015.October.26.16
Cite this Article:
(2015). Clinical significance of CD44 expression in children with hepatoblastoma. Genet. Mol. Res. 14(4): gmr6652. https://doi.org/10.4238/2015.October.26.16
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Abstract

The aim of this study was to investigate the expression of CD44 and its clinical significance in children suffering from hepatoblastoma (HB). CD44 expression was detected with immunohistochemistry staining in 30 samples from hepatoblastoma children and 10 normal liver tissue samples from normal children. The data obtained was statistically analyzed using the chi-square test, using the SPSS (v.11.0) software. The rate of CD44 expression was significantly higher (66.7%) in hepatoblastoma tissues than in normal liver tissues (χ2 = 4.848, P 2 = 5.625, P

The aim of this study was to investigate the expression of CD44 and its clinical significance in children suffering from hepatoblastoma (HB). CD44 expression was detected with immunohistochemistry staining in 30 samples from hepatoblastoma children and 10 normal liver tissue samples from normal children. The data obtained was statistically analyzed using the chi-square test, using the SPSS (v.11.0) software. The rate of CD44 expression was significantly higher (66.7%) in hepatoblastoma tissues than in normal liver tissues (χ2 = 4.848, P 2 = 5.625, P