3'-UTR

Association of MEF2A gene 3'UTR mutations with coronary artery disease

X. C. Huang and Wang, W., Association of MEF2A gene 3'UTR mutations with coronary artery disease, vol. 14, pp. 11073-11078, 2015.

Association of variants in the myocyte enhancer factor 2A (MEF2A) gene and the risk of coronary artery disease (CAD) has drawn much attention but remains controversial. We hypothesized that the 3'-untranslated region (3'-UTR) of this gene could harbor functionally relevant nucleotide changes. Here, we assessed the association between single nucleotide polymorphisms (SNPs) in the 3'-UTR of MEF2A and CAD in the Chinese Han population. A case-control study of 236 CAD patients and 278 controls was carried out.

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