5-HT transporter gene-linked polymorphic region

Relationship between 5-HTTLPR polymorphism and post-stroke depression

W. Y. Guo, Zhang, Z. H., Mu, J. L., Liu, D., Zhao, L., Yao, Z. Y., Song, J. G., Guo, W. Y., Zhang, Z. H., Mu, J. L., Liu, D., Zhao, L., Yao, Z. Y., and Song, J. G., “Relationship between 5-HTTLPR polymorphism and post-stroke depression”, vol. 15, p. -, 2016.

Post-stroke depression (PSD) is a mental illness characterized by subjective feelings of depression, cognitive dysfunction, and decreased interest. The serotoninergic system is involved in the pathogenesis of depressive disorders and is regulated by the serotonin transporter gene. The serotonin transporter-linked polymorphic region (5-HTTLPR) has been examined as a factor associated with depression and other mental disorders. This study was performed to explore the relationship between 5-HTTLPR and PSD in a Han Chinese population.

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