ABO gene

α-1,3-N-acetylgalactose aminotransferase gene 539G>C mutation leads to the A2B isoform

J. J. Lin, Wang, X. D., and Zhu, S. Y., α-1,3-N-acetylgalactose aminotransferase gene 539G>C mutation leads to the A2B isoform, vol. 13, pp. 2987-2993, 2014.

In this study, the phenotypic identification and molecular mechanism of one case of an A2B subtype pedigree was investigated. ABO blood groupings were identified by serological methods and sequence amplification was performed by polymerase chain reaction (PCR) using TA cloning and DNA sequencing analysis to identify the pedigree and the ABO gene haploid of the proband. There were both A and B antigens on the proband's red blood cells, and anti-A1 antibodies were found in the serum.

ABO genotyping in leukemia patients reveals new ABO variant alleles

M. C. Z. Novaretti, Domingues, A. E., Manhani, R., Pinto, E. M., Dorlhiac-Llacer, P. E., and Chamone, D. A. F., ABO genotyping in leukemia patients reveals new ABO variant alleles, vol. 7, pp. 87-94, 2008.

The ABO blood group is the most important blood group system in transfusion medicine and organ transplantation. To date, more than 160 ABO alleles have been identified by molecular investigation. Almost all ABO genotyping studies have been performed in blood donors and families and for investigation of ABO subgroups detected serologically. The aim of the present study was to perform ABO genotyping in patients with leukemia.

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