Achilles tendon

Therapeutic potential of mesenchymal stem cells to treat Achilles tendon injuries

M. H. C. Vieira, Oliveira, R. J., Eça, L. P. M., Pereira, I. S. O., Hermeto, L. C., Matuo, R., Fernandes, W. S., Silva, R. A., and Antoniolli, A. C. M. B., Therapeutic potential of mesenchymal stem cells to treat Achilles tendon injuries, vol. 13, pp. 10434-10449, 2014.

Rupture of the Achilles tendon diminishes quality of life. The gold-standard therapy is a surgical suture, but this presents complications, including wound formation and inflammation. These complications spurred evaluation of the therapeutic potential of mesenchymal stem cells (MSCs) from adipose tissue. New Zealand rabbits were divided into 6 groups (three treatments with two time points each) evaluated at either 14 or 28 days after surgery: cross section of the Achilles tendon (CSAT); CSAT + Suture; and CSAT + MSC.

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