Adipocyte

RNA interference of leptin receptor in chicken adipocytes

A. X. Huang, Li, J. J., Tian, Y., Shen, J. D., Tao, Z. R., Li, G. Q., Lu, L. Z., Fu, Y., and Wu, T. X., RNA interference of leptin receptor in chicken adipocytes, vol. 13, pp. 5901-5907, 2014.

In this study, chicken adipocytes were cultured to evaluate RNA interference by the leptin receptor gene. A small interfering RNA of the leptin receptor gene was synthesized, with a suppression rate of 60% being generated (P peroxisome proliferator-activated receptor γ, fatty acid synthase, adipose triglyceride lipase, and lipoprotein lipase. In addition, a significant increase in the expression of the adiponectin gene was documented.

Adenovirus-mediated interference of FABP4 regulates mRNA expression of ADIPOQ, LEP and LEPR in bovine adipocytes

S. Wei, Zan, L. S., Wang, H. B., Cheng, G., Du, M., Jiang, Z., Hausman, G. J., McFarland, D. C., and Dodson, M. V., Adenovirus-mediated interference of FABP4 regulates mRNA expression of ADIPOQ, LEP and LEPR in bovine adipocytes, vol. 12, pp. 494-505, 2013.

Fatty acid binding protein 4 (FABP4) is an important adipocyte gene, with roles in fatty acid transport and fat deposition in animals as well as human metabolic syndrome. However, little is known about the functional regulation of FABP4 at the cellular level in bovine.

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