Adipose tissue

Developmental methylation pattern regulates porcine GPR120 expression

H. M. Wang, Ma, J. D., Jin, L., Liu, Y. H., Che, T. D., Li, M. Z., Li, X. W., Wang, H. M., Ma, J. D., Jin, L., Liu, Y. H., Che, T. D., Li, M. Z., and Li, X. W., Developmental methylation pattern regulates porcine GPR120 expression, vol. 15, p. -, 2016.

DNA methylation is an important component of the epigenetic machinery and plays a critical role in transcriptional regulation. It mostly occurs in CpG abundant regions, known as CpG islands (CGIs). G protein-coupled receptor 120 (GPR120) functions as an omega-3 fatty acid receptor and is involved in multiple-biological processes, including lipogenesis.

Role of adiponectin in adipose tissue wound healing

C. E. Jin, Xiao, L., Ge, Z. H., Zhan, X. B., and Zhou, H. X., Role of adiponectin in adipose tissue wound healing, vol. 14, pp. 8883-8891, 2015.

The purpose of this study was to investigate the mechanism behind adipose tissue wound healing (ATWH). The preadipocyte cell line 3T3-L1 was cultured and expression of adiponectin receptors (AdipoR1/2) was detected by immunohistochemistry and reverse transcription polymerase chain reaction. The concentration of adiponectin secreted at different cell densities was measured by enzyme-linked immunosorbent assay, while preadipocyte proliferation and migration were determined in vitro by MTT and wound closure assays. AdipoR1/2 were found to be expressed in 3T3-L1 preadipocytes.

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