AGTR1

Analysis of correlations between coronary heart disease and haplotypes of the angiotensin II receptor type 1 (AGTR1) gene

L. J. Duan, Wang, X. D., Duan, L. J., Wang, X. D., Duan, L. J., and Wang, X. D., Analysis of correlations between coronary heart disease and haplotypes of the angiotensin II receptor type 1 (AGTR1) gene, vol. 15, p. -, 2016.

This study aimed to explore correlations between haplotypes of the angiotensin II receptor type 1 (AGTR1) gene and coronary heart disease (CHD). In total, 204 patients with CHD and 206 healthy controls were genotyped using denaturing high-performance liquid chromatography between 2008 and 2014. Five polymorphic loci were found, namely, A-43281G, A-32954G, G-32839A, G-11064A, and A1880G. Likelihood estimates were used to identify haplotypes consisting of the A1166C locus and four of these five loci, then correlations between these haplotypes and CHD were assessed.

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