Analysis of correlations between coronary heart disease and haplotypes of the angiotensin II receptor type 1 (AGTR1) gene
“Analysis of correlations between coronary heart disease and haplotypes of the angiotensin II receptor type 1 (AGTR1) gene”, vol. 15, p. -, 2016.
, This study aimed to explore correlations between haplotypes of the angiotensin II receptor type 1 (AGTR1) gene and coronary heart disease (CHD). In total, 204 patients with CHD and 206 healthy controls were genotyped using denaturing high-performance liquid chromatography between 2008 and 2014. Five polymorphic loci were found, namely, A-43281G, A-32954G, G-32839A, G-11064A, and A1880G. Likelihood estimates were used to identify haplotypes consisting of the A1166C locus and four of these five loci, then correlations between these haplotypes and CHD were assessed.