Expression of M3 acetylcholine receptor in asthmatic mice and bronchial airway remodeling prediction
“Expression of M3 acetylcholine receptor in asthmatic mice and bronchial airway remodeling prediction”, vol. 15, p. -, 2016.
, This study aimed to investigate the role of M3 acetylcholine receptor (M3-AChR) expression in airway remodeling. Additionally, we aimed to evaluate the effects of ipratropium bromide solution inhaled in an early phase of asthma on airway remodeling in ovalbumin (OVA)-sensitized and challenged mice. Thirty BALB/c mice were divided into three groups, namely, control group (saline sensitized/challenged mice), asthma group (OVA sensitized/challenged mice), and treatment group (OVA sensitized/challenged mice treated by ipratropium bromide).