Akirin2 expression

Akirin2 expression in response to vaccine-induced immunity in chicken

C. L. Man, Mu, W. T., Chang, Y., and Zhao, D. X., Akirin2 expression in response to vaccine-induced immunity in chicken, vol. 14, pp. 17489-17495, 2015.

Akirin2 is a nuclear factor that plays an important role in the development and regulation of innate immune response. In this study, akirin2 gene expression in several primary immune organs (liver, thymus, and bursa) of Hi-Line Brown chicken administered with the LoSota vaccine was analyzed during the various stages of increase in Newcastle disease virus antibody titer. The results revealed that akirin2 expression was significantly higher in the liver (P < 0.01) and bursa (P < 0.05) of vaccinated chicken 7 and 14 days post-immunization, respectively.

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