Androgenic hormone

HNF1b is involved in prostate cancer risk via modulating androgenic hormone effects and coordination with other genes

Y. L. Hu, Zhong, D., Pang, F., Ning, Q. Y., Zhang, Y. Y., Li, G., Wu, J. Z., and Mo, Z. N., HNF1b is involved in prostate cancer risk via modulating androgenic hormone effects and coordination with other genes, vol. 12, pp. 1327-1335, 2013.

Prostate cancer is one of the most commonly diagnosed male malignancies. Genome wide association studies have revealed HNF1b to be a major risk gene for prostate cancer susceptibility. We examined the mechanisms of involvement of HNF1b in prostate cancer development. We integrated data from Gene Expression Omnibus prostate cancer genes from the Dragon Database of Genes Implicated in Prostate Cancer, and used meta-analysis data to generate a panel of HNF1b-associated prostate cancer risk genes.

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