Angiotensin-II

Effects of intra- and extracellular factors on anti-aging klotho gene expression

K. Turan and Ata, P., Effects of intra- and extracellular factors on anti-aging klotho gene expression, vol. 10, pp. 2009-2023, 2011.

Inactivation of the klotho gene in mice causes serious systemic disorders, resembling human aging. However, at the molecular level, its action mechanisms are not well understood. The stimulatory or inhibitory effects of cis- and trans-regulatory factors on the klotho gene expression are also still unclear. We studied the effects of intra- and extracellular factors on human klotho gene expression.

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