Anti-microbial peptide

Characteristics of cathelicidin-Bg, a novel gene expressed in the ear-side gland of Bufo gargarizans

F. Gao, Xu, W. F., Tang, L. P., Wang, M. M., Wang, X. J., Qian, Y. C., Gao, F., Xu, W. F., Tang, L. P., Wang, M. M., Wang, X. J., and Qian, Y. C., Characteristics of cathelicidin-Bg, a novel gene expressed in the ear-side gland of Bufo gargarizans, vol. 15, p. -, 2016.

The traditional Chinese medicine Chan Su (toad venom) comprises dried secretions of the ear-side gland of Bufo gargarizans. Chan Su is known for its small molecular components, which include telocinobufagin, marinobufagin, and bufalin, while in other amphibians, studies mainly focus on peptide components. Until recently, no genes expressed in the ear-side gland of B. gargarizans gland had been cloned. In this study, cathelicidin-Bg, a coding sequence of anti-microbial peptide (AMP), was cloned.

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