AQP-1

Protective effect and mechanism of hydrogen treatment on lung epithelial barrier dysfunction in rats with sepsis

L. - D. Liu, Wu, X. - Y., Tao, B. - D., Wang, N., Zhang, J., Liu, L. - D., Wu, X. - Y., Tao, B. - D., Wang, N., Zhang, J., Liu, L. - D., Wu, X. - Y., Tao, B. - D., Wang, N., and Zhang, J., Protective effect and mechanism of hydrogen treatment on lung epithelial barrier dysfunction in rats with sepsis, vol. 15, p. -, 2016.

This study aimed to explore the protective effect of hydrogen and to investigate the underlying mechanism of its preliminary effect on the alveolar epithelial barrier function in septic rats. Forty-five male Sprague-Dawley rats were divided randomly into three groups (N = 15): control [saline injection (intraperitoneal, ip), air drawing; SA], acute lung injury group [lipopolysaccharide (LPS) injection (ip, 15 mg/kg), air drawing; LA], and acute lung injury combined with hydrogen drawing group [LPS injection (ip, 15 mg/kg), 2% hydrogen drawing; LH].

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