Association

Characterization and identification of ISSR markers associated with oil content in sea buckthorn berries

J. Ding, Ruan, C. J., Guan, Y., Shan, J. Y., Li, H., Bao, Y. H., Ding, J., Ruan, C. J., Guan, Y., Shan, J. Y., Li, H., and Bao, Y. H., “Characterization and identification of ISSR markers associated with oil content in sea buckthorn berries”, vol. 15, p. -, 2016.

Bioactive oils extracted from sea buckthorn (Hippophae rhamnoides) berries contain highly nutritional and medicinal compounds; however, the oil contents of sea buckthorn berries are very low. Thirteen inter-simple sequence repeat (ISSR) primers were used to identify markers associated with oil content of dry pulp in 51 cultivars and lines, which clustered into three major groups based on 137 polymorphic markers. Dry pulp oil contents in 45 cultivars and lines in Group I ranged from 6.6 to 33.1%; these accessions belonged to H.

Polymorphisms in GJA1 and their association with growth traits in chicken

M. Shahjahan, Liu, R. R., Zhao, G. P., Zhang, J. J., Zheng, M. Q., Li, Q. H., and Wen, J., “Polymorphisms in GJA1 and their association with growth traits in chicken”, vol. 14, pp. 18839-18850, 2015.

This study aimed to screen single nucleotide polymorphisms (SNPs) in the chicken gap junction protein alpha 1 (GJA1) gene, and to investigate their association with five growth traits measured in 269 chickens encompassing Chinese indigenous Beijing-You (BJY) and commercial Cobb broiler (CB) populations. Four variants were detected in the chicken GJA1 gene, in which one synonymous mutation was located in an exon (C61223231T or c.-1110 C>T), two in an intron (A61229799C or c.5460 A>C, T61229928A or c.5589 T>A) and one in the promoter (A61230599C or c.

Association between TAP1 gene polymorphisms and alopecia areata in a Korean population

H. K. Kim, Lee, H., Lew, B. L., Sim, W. Y., Kim, Y. O., Lee, S. W., Lee, S., Cho, I. K., Kwon, J. T., and Kim, H. J., “Association between TAP1 gene polymorphisms and alopecia areata in a Korean population”, vol. 14, pp. 18820-18827, 2015.

The transporter 1 ATP-binding cassette sub-family B (MDR/TAP) gene (TAP1) is located in the major histocompatibility complex class II region, and forms a heterodimer that plays a key role in endogenous antigen presentation pathways. Investigation of polymorphisms identified in these loci has revealed an association with several autoimmune disorders. Alopecia areata (AA) is a common autoimmune disease resulting from T cell-induced damage to hair follicles.

Association of TNF-α G308A gene polymorphism in essential hypertensive patients without type 2 diabetes mellitus

N. Ghodsian, Akhlaghi, M., Ramachandran, V., Heidari, F., Haghvirdizadeh, P., Eshkoor, S. A., Etemad, A., Jamaluddin, J. A., and Ismail, P., “Association of TNF-α G308A gene polymorphism in essential hypertensive patients without type 2 diabetes mellitus”, vol. 14, pp. 18974-18979, 2015.

This study aims to investigate the effects of tumor necrosis factor alpha (TNF-α) G308A gene polymorphism on essential hypertension (EHT) with or without type 2 diabetes mellitus (T2DM). The project was conducted on buccal epithelial and blood cells for case and control patients, respectively. Epithelial cells were obtained from the inner part of the cheeks. Techniques including DNA extraction, polymerase chain reaction (PCR), and restriction fragment length polymorphism (RFLP) were utilized to assess biomarkers of DNA damage.

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