AZF deletion

Association study between Y-chromosome haplogroups and susceptibility to spermatogenic impairment in Han People from southwest China

J. Ran, Han, T. T., Ding, X. P., Wei, X., Zhang, L. Y., Zhang, Y. P., Li, T. J., Nie, S. S., and Chen, L., Association study between Y-chromosome haplogroups and susceptibility to spermatogenic impairment in Han People from southwest China, vol. 12, pp. 59-66, 2013.

The non-recombining portion of the Y-chromosome contains numerous polymorphisms; therefore, it is now the most informative haplotyping system with wide-ranging applications. Idiopathic azoospermia and oligospermia are among the most important causes of male infertility. Different haplogroups may have different genetic backgrounds, which may be either susceptible or unsusceptible to idiopathic azoospermia or oligospermia. This study investigated the possible association between Y-chromosome haplogroup distribution and susceptibility to spermatogenic impairment.

Subscribe to AZF deletion