Betweenness

Mining topological structures of protein-protein interaction networks for human brain-specific genes

W. J. Cui, Gong, X. J., Yu, H., and Zhang, X. C., Mining topological structures of protein-protein interaction networks for human brain-specific genes, vol. 14, pp. 12437-12445, 2015.

Compared to other placental mammals, humans have unique thinking and cognitive abilities because of their developed cerebral cortex composed of billions of neurons and synaptic connections. As the primary effectors of the mechanisms of life, proteins and their interactions form the basis of cellular and molecular functions in the living body. In this paper, we developed a pipeline for mining topological structures, identifying functional modules, and analyzing their functions from publically available datasets.

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