Biomarker

Expression of microRNA-106b and its clinical significance in cutaneous melanoma

N. Lin, Zhou, Y., Lian, X., and Tu, Y., Expression of microRNA-106b and its clinical significance in cutaneous melanoma, vol. 14, pp. 16379-16385, 2015.

MicroRNA-106b (miR-106b) is overexpressed in various types of cancers and is associated with the regulation of carcinogenic processes. However, its clinical significance in cutaneous melanoma has not been reported. qRT-PCR was performed to examine the expression of miR-106b in 15 cases of dysplastic nevi, 17 cases of melanoma metastases, and 97 cases of primary cutaneous melanoma tissue samples. Survival rate was determined with Kaplan-Meier and statistically analyzed with the log-rank method between groups. Survival data were evaluated through multivariate Cox regression analysis.

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