Bone morphogenetic protein 2

Bone morphogenetic protein 2 and decorin expression in old fracture fragments and surrounding tissues

X. G. Han, Wang, D. K., Gao, F., Liu, R. H., and Bi, Z. G., Bone morphogenetic protein 2 and decorin expression in old fracture fragments and surrounding tissues, vol. 14, pp. 11063-11072, 2015.

Bone morphogenetic protein 2 (BMP-2) can promote fracture healing. Although the complex role BMP-2 in bone formation is increasingly understood, the role of endogenous BMP-2 in nonunion remains unclear. Decorin (DCN) can promote the formation of bone matrix and calcium deposition to control bone morphogenesis. In this study, tissue composition and expression of BMP-2 and DCN were detected in different parts of old fracture zones to explore inherent anti-fibrotic ability and osteogenesis.

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