Effect of gene transfection timing on TGF-β1 expression in rabbit mandibular distraction gap.
“Effect of gene transfection timing on TGF-β1 expression in rabbit mandibular distraction gap.”, Genet Mol Res, vol. 16, no. 2, 2017.
, Bone morphogenetic protein 2 (BMP-2) can promote fracture healing. Although the complex role BMP-2 in bone formation is increasingly understood, the role of endogenous BMP-2 in nonunion remains unclear. Decorin (DCN) can promote the formation of bone matrix and calcium deposition to control bone morphogenesis. In this study, tissue composition and expression of BMP-2 and DCN were detected in different parts of old fracture zones to explore inherent anti-fibrotic ability and osteogenesis.