Cancer

Association between the WRAP53 gene rs2287499 C>G polymorphism and cancer risk: A meta-analysis

H. Y. Cao, Wang, S., Zhang, Z. Y., Lou, J. Y., Cao, H. Y., Wang, S., Zhang, Z. Y., and Lou, J. Y., Association between the WRAP53 gene rs2287499 C>G polymorphism and cancer risk: A meta-analysis, vol. 15, p. -, 2016.

The TP53 5'-untranslated region flanking the gene WRAP53 (also known as WDR79 and TCAB1) has been hypothesized to be associated with cancer risk due to its critical function in regulating p53 levels. In this review, we analyzed the association between the WRAP53 gene rs2287499 C>G polymorphism and risk of cancer using five case-control studies, comprising seven datasets. All analyses were performed using RevMan software. In the overall analysis, no significant association between rs2287499 and risk of cancer was found.

Subscribe to Cancer