Carbon monoxide poisoning

Association of the genes for tumor necrosis factor-α and myelin basic protein with delayed encephalopathy after acute carbon monoxide poisoning

S. G. Li, Li, W. Q., Wang, J. K., Zhang, H. Y., Li, W., Zhang, P., Wang, X. H., Zhang, H. X., Gu, J. P., and Gu, R. J., Association of the genes for tumor necrosis factor-α and myelin basic protein with delayed encephalopathy after acute carbon monoxide poisoning, vol. 11, pp. 4479-4486, 2012.

There is structural damage to myelin and secondary immune injury in the development of delayed encephalopathy after acute carbon monoxide (CO) poisoning (DEACMP). In order to assess the role of genetic factors in this mechanism, we studied the association between tumor necrosis factor-α308 (TNF-α308) and myelin basic protein (MBP) 5ꞌ-side tetranucleotide repetitive sequence (TGGA) n gene polymorphism and DEACMP.

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