Carotid artery atherosclerotic disease

Association of paraoxonase polymorphisms with carotid artery atherosclerosis in essential hypertension patients

L. Han, Xu, X. J., Liang, X. H., and Ma, J., Association of paraoxonase polymorphisms with carotid artery atherosclerosis in essential hypertension patients, vol. 12, pp. 5174-5185, 2013.

We investigated the relationships between paraoxonase genetic polymorphisms and essential hypertension in carotid artery atherosclerotic patients. The study included 353 Han participants and 240 Uighur participants from Xinjiang; they were further divided into two groups: essential hypertension with carotid artery atherosclerosis (CAAD group) and essential hypertension without carotid artery atherosclerosis (control group). Genotypes were detected by PCR, followed by restriction analyses with specific endonucleases.

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