CD8 T cell

Frequency of TLR4 (1063A/G and 1363C/T) polymorphisms in healthy and HIV-infected Omani individuals and their relationship to viral load and T cell count

E. A. Said, Al-Yafei, F., Zadjali, F., Al-Balushi, M. S., Hasson, S. S., Al-Mahroqi, S. H., Koh, C. Y., Al-Naamani, K., Al-Busaidi, J. Z., Idris, M. A., Balkhair, A., Al-Jabri, A. A., Said, E. A., Al-Yafei, F., Zadjali, F., Al-Balushi, M. S., Hasson, S. S., Al-Mahroqi, S. H., Koh, C. Y., Al-Naamani, K., Al-Busaidi, J. Z., Idris, M. A., Balkhair, A., Al-Jabri, A. A., Said, E. A., Al-Yafei, F., Zadjali, F., Al-Balushi, M. S., Hasson, S. S., Al-Mahroqi, S. H., Koh, C. Y., Al-Naamani, K., Al-Busaidi, J. Z., Idris, M. A., Balkhair, A., and Al-Jabri, A. A., Frequency of TLR4 (1063A/G and 1363C/T) polymorphisms in healthy and HIV-infected Omani individuals and their relationship to viral load and T cell count, vol. 15, p. -, 2016.

Toll-like receptors (TLRs) are essential elements of the innate immune response to different infections including the infection with human immunodeficiency virus (HIV). Single nucleotide polymorphisms (SNPs) in TLRs such as TLR4 1063A/G and 1363C/T have been found to be associated with changes in CD4 count, viral load (VL), and disease progression during HIV infection. However, the association of these SNPs with the pathogenesis during HIV infection is controversial.

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