Cerebrospinal fluid

Diagnostic value of cytological and microbiological methods in cryptococcal meningitis

M. Zhang, Li, J. C., Lin, H., Zhang, W., Lin, M., Wu, L., Liu, W., Mu, J. S., Ye, J. X., and Cui, X. P., Diagnostic value of cytological and microbiological methods in cryptococcal meningitis, vol. 13, pp. 9253-9261, 2014.

The aim of this study was to investigate diagnostic methods for cryptococcal meningitis (CM). A retrospective analysis was conducted for 31 patients with CM confirmed by etiologic detection of cerebrospinal fluid in our hospital in the past 5 years. Nineteen cases in 31 patients were confirmed with CM in the first diagnosis, with a misdiagnosis rate of 38.7%. The positive rates of cryptococcus detection in cerebrospinal fluid with May-Grünwald-Giemsa (MGG)-, ink-, and Alcian blue-staining methods were 86.9, 70.9, and 80.6%, respectively.

Differentiation of neonatal dorsal root ganglion-derived neural stem cells into oligodendrocytes after intrathecal transplantation into a cauda equina lesion model

Z. Y. Fu, Shi, J. G., Liu, N., Jia, L. S., Yuan, W., and Wang, Y., Differentiation of neonatal dorsal root ganglion-derived neural stem cells into oligodendrocytes after intrathecal transplantation into a cauda equina lesion model, vol. 12, pp. 6092-6102, 2013.

Cauda equina syndrome (CES) is characterized by varying patterns of low back pain, sciatica, lower extremity sensorimotor loss, and bowel and bladder dysfunction. The prognosis for complete recovery of CES is dependent on not only the time before surgical intervention with decompression but also the severity of the nerve damage. Delayed or severe nerve compression impairs the capability of nerve regeneration. Transplantation of neural stem cells (NSCs) may facilitate axon regeneration and functional recovery in a spectrum of neurological disorders.

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