Chicken embryo fibroblast

Gene expression changes in chicken NLRC5 signal pathway associated with in vitro avian leukosis virus subgroup J infection

L. L. Qiu, Xu, L., Guo, X. M., Li, Z. T., Wan, F., Liu, X. P., Chen, G. H., Chang, G. B., Qiu, L. L., Xu, L., Guo, X. M., Li, Z. T., Wan, F., Liu, X. P., Chen, G. H., Chang, G. B., Qiu, L. L., Xu, L., Guo, X. M., Li, Z. T., Wan, F., Liu, X. P., Chen, G. H., and Chang, G. B., “Gene expression changes in chicken NLRC5 signal pathway associated with in vitro avian leukosis virus subgroup J infection”, vol. 15, p. -, 2016.

Nucleotide-binding oligomerization domain-like receptors (NLRs) play a key role in the innate immune response as pattern-recognition receptors. However, the role of NLRC5, which is a member of the NLR family, in NF-κB activation and MHC-I expression remains debatable. Infection with the J group avian leukosis virus (ALV-J) can result in immunosuppression and a subsequent increase in susceptibility to secondary infection. This results in huge economic losses to the poultry industry worldwide.

microRNAs in avian influenza virus H9N2-infected and non-infected chicken embryo fibroblasts

X. Peng, Gao, Q. S., Zhou, L., Chen, Z. H., Lu, S., Huang, H. J., Zhan, C. Y., and Xiang, M., “microRNAs in avian influenza virus H9N2-infected and non-infected chicken embryo fibroblasts”, vol. 14, pp. 9081-9091, 2015.

There is limited information about microRNAs (miRNAs) in H9N2 subtype influenza virus-infected chicken cells or tissues. In this study, 10,487,469 and 13,119,795 reads were obtained from infected and non-infected chicken embryo fibroblasts, respectively. Seven hundred and thirty-six and 1004 miRNAs, including mature miRNAs and precursors, were obtained from the infected and non-infected fibroblasts, respectively.