Chinese Han

Association of CD14 G(-1145)A and C(-159)T polymorphisms with reduced risk for tuberculosis in a Chinese Han population

M. Y. Zhao, Xue, Y., Zhao, Z. Q., Li, F. J., Fan, D. P., Wei, L. L., Sun, X. J., Zhang, X., Wang, X. C., Zhang, Y. X., and Li, J. C., Association of CD14 G(-1145)A and C(-159)T polymorphisms with reduced risk for tuberculosis in a Chinese Han population, vol. 11, pp. 3425-3431, 2012.

Although the role of CD14 in mediating signals from Toll-like receptors to recognize Mycobacterium tuberculosis is known, how polymorphisms in this gene affect the susceptibility to develop tuberculosis are still not clear. We examined whether single nucleotide polymorphisms at positions -1145 and -159 in the promoter region of the CD14 gene are associated with tuberculosis in a Chinese Han population in a case-control study of 432 Chinese patients with tuberculosis and 404 ethnically matched healthy controls.

Structure and polymorphism of 16 novel Y-STRs in Chinese Han Population

G. Q. Zhang, Yang, S. Y., Niu, L. L., and Guo, D. W., Structure and polymorphism of 16 novel Y-STRs in Chinese Han Population, vol. 11, pp. 4487-4500, 2012.

Y-chromosome short tandem repeats (Y-STRs) are useful tools for identifying paternity origin and male-female mixed samples because of their male-specificity, haploid inheritance and relatively simplicity. We focused on novel Y-STRs deposited in the human Genome database from DYS708 to DYS726. We typed 16 male-specific Y-STRs from males of a Chinese Han population residing in Shanxi Province (north China), including DYS708-719, DYS721-723, and DYS726, but failed in typing DYS720, DYS724 and DYS725.

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