Chitosan

Evaluation of bone matrix gelatin/fibrin glue and chitosan/gelatin composite scaffolds for cartilage tissue engineering

Z. H. Wang, Zhang, J., Zhang, Q., Gao, Y., Yan, J., Zhao, X. Y., Yang, Y. Y., Kong, D. M., Zhao, J., Shi, Y. X., Li, X. L., Wang, Z. H., Zhang, J., Zhang, Q., Gao, Y., Yan, J., Zhao, X. Y., Yang, Y. Y., Kong, D. M., Zhao, J., Shi, Y. X., and Li, X. L., Evaluation of bone matrix gelatin/fibrin glue and chitosan/gelatin composite scaffolds for cartilage tissue engineering, vol. 15, p. -, 2016.

This study was designed to evaluate bone matrix gelatin (BMG)/fibrin glue and chitosan/gelatin composite scaffolds for cartilage tissue engineering. Chondrocytes were isolated from costal cartilage of Sprague-Dawley rats and seeded on BMG/fibrin glue or chitosan/gelatin composite scaffolds. After different in vitro culture durations, the scaffolds were subjected to hematoxylin and eosin, Masson’s trichrome, and toluidine blue staining, anti-collagen II and anti-aggrecan immunohistochemistry, and scanning electronic microscopy (SEM) analysis.

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