Upregulation of fibroblast growth factor 1 in the synovial membranes of patients with late stage osteoarthritis
“Upregulation of fibroblast growth factor 1 in the synovial membranes of patients with late stage osteoarthritis”, vol. 14, pp. 11191-11199, 2015.
, Osteoarthritis (OA) is a degenerative disease of the systemic joint that involves multiple cytokines and growth factors. Fibroblast growth factor 1 (FGF-1) is increased in patients with rheumatic arthritis. The aim of this study was to determine whether the expression and secretion of FGF-1 differed in synovial tissue from patients with late stage OA from that in normal tissues. We selected eight patients with late stage OA and eight healthy donors for this study.