B-type natriuretic peptide and cirrhosis progression

L. Y. Shi, Jin, R., Lin, C. J., Wu, J. S., Chen, X. W., Yu, Z., and Zhang, P. C., B-type natriuretic peptide and cirrhosis progression, vol. 14, pp. 5188-5196, 2015.

Brain natriuretic peptide (BNP) is used as a marker of cardiac dysfunction to predict heart failure mortality. The significance of the prognostic ability of BNP for liver cirrhosis remains unknown, although the levels of BNP seen in cirrhosis are high. We aimed to determine whether the BNP level is related to the stage of cirrhosis and could serve as a prognostic marker of cirrhosis (predict the 1-year all-cause mortality). We recruited 92 patients at different stages of cirrhosis and 81 controls matched by age and gender for this study.

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