Collagen IX

The role of smoking status and collagen IX polymorphisms in the susceptibility to cervical spondylotic myelopathy

Z. C. Wang, Shi, J. G., Chen, X. S., Xu, G. H., Li, L. J., and Jia, L. S., The role of smoking status and collagen IX polymorphisms in the susceptibility to cervical spondylotic myelopathy, vol. 11, pp. 1238-1244, 2012.

We investigated a possible association of collagen IX tryptophan (Trp) alleles (Trp2 and Trp3) and smoking with cervical spondylotic myelopathy (CSM) in 172 Chinese patients and 176 age- and gender-matched controls. The smoking status was evaluated by smoking index (SI). The CSM cases had a significantly higher prevalence of Trp2 alleles (Trp2+) than controls (19.8 vs 6.2%, P = 0.002), but the prevalence of Trp3 alleles (Trp3+) was similar between the two groups (23.3 vs 21.6%, P = 0.713).

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