Congenital biliary atresia

Expression of transforming growth factor-β1 and connective tissue growth factor in congenital biliary atresia and neonatal hepatitis liver tissue

F. B. Li, Zhao, H., Peng, K. R., Gao, Z. G., Huang, S. J., Tou, J. F., Shu, X. L., Gu, W. Z., Li, F. B., Zhao, H., Peng, K. R., Gao, Z. G., Huang, S. J., Tou, J. F., Shu, X. L., and Gu, W. Z., Expression of transforming growth factor-β1 and connective tissue growth factor in congenital biliary atresia and neonatal hepatitis liver tissue, vol. 15, p. -, 2016.

We investigated the expression of transforming growth factor-β1 (TGF-β1) and connective tissue growth factor (CTGF) in the liver tissue of infants with congenital biliary atresia and neonatal hepatitis, as well as the relationship between the expression of the two factors and liver fibrosis. Thirty-six infants who met the cholestasis criteria were classified into congenital biliary atresia and neonatal hepatitis groups. All specimens were stained with hematoxylin and eosin and Masson’s trichrome, and the degree of liver fibrosis was assessed.

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