Coronary heart disease

Correlation between polymorphisms in the estrogen receptor α gene and coronary heart disease: A meta-analysis

W. Zhou, He, K. H., Chen, M. H., Zhou, W., He, K. H., and Chen, M. H., Correlation between polymorphisms in the estrogen receptor α gene and coronary heart disease: A meta-analysis, vol. 15, p. -, 2016.

The aim of this study was to conduct a systematic evaluation the correlation between polymorphisms in the estrogen receptor α gene (ESRα) and coronary heart disease susceptibility. Case-control studies until August 2015 analyzing the correlation between the ESRα PvuII T/C polymorphism and coronary heart disease were obtained from various electronic databases (CBM, CNKI, Wanfang Data, VIP, and MEDLINE, Cochrane Library, Embase, Springer, and Ovid. The data obtained from these studies were evaluated and valid data was extracted.

Correlation between the 677C>T polymorphism in the methylene tetrahydrofolate reductase gene and serum homocysteine levels in coronary heart disease

Y. Y. Chen, Wang, B. N., Yu, X. P., Chen, Y. Y., Wang, B. N., Yu, X. P., Chen, Y. Y., Wang, B. N., and Yu, X. P., Correlation between the 677C>T polymorphism in the methylene tetrahydrofolate reductase gene and serum homocysteine levels in coronary heart disease, vol. 15, p. -, 2016.

The aim of the current study was to explore the correlation between serum homocysteine (HCY) levels and the methylene tetrahydrofolate reductase (MTHFR) gene 677C/T polymorphism and coronary heart disease (CHD). We consecutively enrolled 208 patients with CHD confirmed by CTA or coronary angiography from our hospital. An additional 200 healthy volunteers were enrolled as the control group. Serum HCY levels, MTHFR C677T genotype, and other related indicators were evaluated for the two groups.

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