CpG ODN

CpG ODN 1826 enhances radiosensitivity of the human lung cancer cell line A549 in a rat model

W. Yan, Sun, T. - Y., Yang, C. - M., Jia, M., Li, J., Tang, H. - L., and Zhou, Y. - F., CpG ODN 1826 enhances radiosensitivity of the human lung cancer cell line A549 in a rat model, vol. 14, pp. 9804-9812, 2015.

This study investigated the effects of CpG ODN1826 plus radiotherapy (RT) on tumor growth and angiogenesis of subcutaneous tumor in a rat model. Four treatment groups were tested in which rats were injected with 100 μL CpG ODN1826 (1 μg/μL) or 100 μL vehicle, with and without exposure to 8 Gy after 2 h. At 7 days after inoculation of lung cancer cells, drugs were injected in the tumor and radiation was administered over 5 days, after which the rate of tumor inhibition was calculated.

Subscribe to CpG ODN