Cytokines

Effects of flurbiprofen axetil on postoperative serum IL-2 and IL-6 levels in patients with colorectal cancer

W. W. Jiang, Wang, Q. H., Peng, P., Liao, Y. J., Duan, H. X., Xu, M., Li, Y., and Zhang, P. B., “Effects of flurbiprofen axetil on postoperative serum IL-2 and IL-6 levels in patients with colorectal cancer”, vol. 14, pp. 16469-16475, 2015.

We explored the effects of flurbiprofen axetil on interleukin (IL)-2 and IL-6 levels in postoperative patients with colorectal cancer. A total of 120 patients (American Society of Anesthesiologists I and II) scheduled to undergo colorectal cancer surgery were randomly divided into 3 groups (N = 40 in each group): flurbiprofen axetil group (group F), morphine group (group M), and tramadol group (group T). Group M received 0.1 mg/kg morphine, group T received 1.5 mg/kg tramadol, and group F received 1.5 mg/kg flurbiprofen axetil.

Relationship between UV-irradiated HaCaT cell cytokines and Th1/Th2 imbalance

H. Y. Li, Zhang, F. R., and Deng, D. Q., “Relationship between UV-irradiated HaCaT cell cytokines and Th1/Th2 imbalance”, vol. 14, pp. 7976-7985, 2015.

We have previously found that an imbalance of Tc1/Tc2 T cell subtypes in vivo impacts the development of photodermatitis. The aim of this study was to investigate the relationship between cytokines derived from keratinocytes exposure to UV and the imbalance of Th subgroups. We used different doses of UVA and UVB to irradiate HaCaT cells. Twelve hours after irradiation, the expression of IL-10R, IL-4R, IL-12R, and IFN-γR proteins was observed using the S-P method, and the percentage of positive cells calculated.