Cytomegalovirus

Genetic mechanism associated with congenital cytomegalovirus infection and analysis of effects of the infection on pregnancy outcome

J. M. Li, Zhang, H. F., Zhang, X. Q., Huang, G. L., Huang, H. Z., and Yu, W. W., Genetic mechanism associated with congenital cytomegalovirus infection and analysis of effects of the infection on pregnancy outcome, vol. 14, pp. 13247-13257, 2015.

We aimed to compare the diagnostic value of various detection methods for cytomegalovirus (CMV) infection, to investigate the genetic mechanism associated with CMV infection in pregnant women, and to analyze the risk of sequelae development in fetuses with CMV infection. A total of 300 participants who had the same immunosuppressive regimen and received preemptive therapy for CMV infection were prospectively enrolled in this study; they included 289 vaccine trial participants. The gB-absorbed CMV IgG assay was performed for each vaccine trial participant.

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