Dihydromyricetin induces cell apoptosis via a p53-related pathway in AGS human gastric cancer cells
“Dihydromyricetin induces cell apoptosis via a p53-related pathway in AGS human gastric cancer cells”, vol. 14, pp. 15564-15571, 2015.
, The aim of the present study was to determine the antiproliferative and pro-apoptotic effects of dihydromyricetin (DHM) on the AGS human gastric cancer cells and their underlying mechanisms. The effects of DHM on AGS cells were evaluated by using 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), lactate dehydrogenase, and Annexin V/propidium iodide (PI) double-staining assays. The underlying mechanisms were determined by using quantitative real-time polymerase chain reaction.