Pedigrees of infertile Chinese men with Y chromosome microdeletions derived from natural transmission and de novo mutation
“Pedigrees of infertile Chinese men with Y chromosome microdeletions derived from natural transmission and de novo mutation”, vol. 14, pp. 1932-1941, 2015.
, Y chromosome microdeletions can cause male infertility and are classified as natural transmission and de novo mutations. To examine the source of these deletions in Chinese men and to provide a theoretical and laboratory basis for genetic counseling, patients from Northeast China with primary male infertility (N = 22) and their fathers were investigated. Karyotype analysis was performed on peripheral blood lymphocytes using standard G-banding.