Protein-protein interaction network and significant gene analysis of osteoporosis
“Protein-protein interaction network and significant gene analysis of osteoporosis”, vol. 12, pp. 4751-4759, 2013.,
This study used DNA microarray data to identify differentially expressed genes of osteoporosis and provide useful information for treatments of the disease. We downloaded gene expression data of Osteoporosis GSE35956 from the Gene Expression Omnibus database, which included five normal and five osteoporosis samples. We then identified the differentially expressed genes between normal and disease samples using the R language software, and constructed the protein interaction network. DAVID was used to perform the biological process enrichment and KEGG pathway cluster analyses.