DHRS4 gene cluster

CpG island evolution in the mammalian DHRS4 gene cluster and its role in the regulation of gene transcription

Z. Su, Liu, G., Song, X., Liang, B., Chang, X., Huang, D., Su, Z., Liu, G., Song, X., Liang, B., Chang, X., and Huang, D., CpG island evolution in the mammalian DHRS4 gene cluster and its role in the regulation of gene transcription, vol. 15, p. -, 2016.

The dehydrogenase/reductase (SDR family) member 4 (DHRS4) gene is copied during mammalian evolution; therefore, while only one DHRS4 gene is expressed in the mouse genome, the gene cluster consists of two (DHRS4 and DHRS4L1) and three (DHRS4, DHRS4L2, and DHRS4L1) copies in chimpanzees and humans, respectively.

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