Diabetic nephropathy

Effect of 1,25-(OH)2D3 and lipopolysaccharide on mononuclear cell inflammation in type 2 diabetes mellitus and diabetic nephropathy uremia

E. L. Wu, Cui, H. X., Wu, E. L., and Cui, H. X., Effect of 1,25-(OH)2D3 and lipopolysaccharide on mononuclear cell inflammation in type 2 diabetes mellitus and diabetic nephropathy uremia, vol. 15, p. -, 2016.

The prevention and treatment of type-2 diabetes mellitus (T2DM) and diabetic nephropathy (DN), which are disorders with high incidence rates, is of primary importance. In this study, we analyzed the effect of 1,25-(OH)2D3 and lipopolysaccharide (LPS) in combination with interleukin (IL)-15 on the inflammatory immune response and expression of vitamin D receptor (VDR) in mononuclear cells of T2DM and DN uremia (DNU) patients.

Association between interleukin-10 gene polymorphisms and susceptibility to diabetic nephropathy in a Chinese population

D. H. Ma, Xu, Q. Y., Liu, Y., Zhai, Q. Q., Guo, M. H., Ma, D. H., Xu, Q. Y., Liu, Y., Zhai, Q. Q., and Guo, M. H., Association between interleukin-10 gene polymorphisms and susceptibility to diabetic nephropathy in a Chinese population, vol. 15, p. -, 2016.

In this study, we investigated the association between the interleukin (IL)-10 -592C/A, -819C/T, and -1082G/A genetic variations and susceptibility to diabetic nephropathy in a Chinese population. The IL-10 -592C/A, -819C/T, and -1082G/A polymorphisms were genotyped in diabetic nephropathy patient and control samples by polymerase chain reaction-restriction fragment length polymorphism. The results were then statistically analyzed using SPSS 17.0.

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