Dickkopf-1

Serum Dickkopf-1 levels as a clinical and prognostic factor in patients with bladder cancer

D. K. Sun, Wang, L., Wang, J. M., and Zhang, P., Serum Dickkopf-1 levels as a clinical and prognostic factor in patients with bladder cancer, vol. 14, pp. 18181-18187, 2015.

Dickkopf-1 (DKK-1) is a secreted protein that inhibits Wnt signaling. However, the clinical significance and prognostic value of serum DKK-1 levels have not been previously investigated in bladder cancer in Chinese patients. Blood samples were taken from 94 consecutive patients diagnosed with bladder cancer and 60 healthy control subjects. Serum DKK-1 expression levels were measured by enzyme-linked immunosorbent assay according to the manufacturer’s directions.

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