Systematic tracking of altered modules identifies disrupted pathways in teratozoospermia
“Systematic tracking of altered modules identifies disrupted pathways in teratozoospermia”, vol. 15, p. -, 2016.
, The objective of this study was to identify disrupted pathways in teratozoospermia by systematically tracking dysregulated modules in reweighted protein-protein interaction (PPI) networks. We inferred and reweighted the PPI networks of normal and teratozoospermia groups based on Spearman correlation coefficients. Modules in the PPI networks were explored via a clique-merging algorithm and altered modules were identified based on maximum weight bipartite matching.