DKK4 gene

Novel SNPs in the exon region of bovine DKK4 gene and their association with body measurement traits in Qinchuan cattle

J. B. Gao, Li, Y. K., Yang, N., Ma, X. H., Adoligbe, C., Jiang, B. J., Fu, C. Z., Cheng, G., and Zan, L. S., Novel SNPs in the exon region of bovine DKK4 gene and their association with body measurement traits in Qinchuan cattle, vol. 12, pp. 6664-6672, 2013.

The aim of this study was to determine whether single nucleotide polymorphisms (SNPs) of bovine Dickkopf homolog 4 (DKK4) are associated with body measurement traits in Qinchuan cattle. By using PCR-SSCP technology and DNA sequencing, we discovered 5 DKK4 SNPs in Qingchuan cattle, including -65G>A and -77G>T in the 5ꞌ-untranslated region, 1532C>G and 1533T>C in exon 2, and 2088C>T in exon 3. The sequencing map showed that 1532C>G and 1533T>C were in close linkage disequilibrium and were treated as 1532C>G-1533T>C in this study.

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