DNA methylation

Changes in methylation of genomic DNA from chicken immune organs in response to H5N1 influenza virus infection

Y. H. Zhang, Meng, J. L., Gao, Y., Zhang, J. Y., Niu, S. L., Yu, X. Z., Li, Y. B., Guan, Y. T., Sun, B. X., Zhao, Z. H., Zhang, Y. H., Meng, J. L., Gao, Y., Zhang, J. Y., Niu, S. L., Yu, X. Z., Li, Y. B., Guan, Y. T., Sun, B. X., and Zhao, Z. H., Changes in methylation of genomic DNA from chicken immune organs in response to H5N1 influenza virus infection, vol. 15, p. -, 2016.

DNA methylation is an important epigenetic modification in eukaryotes, which plays a significant role in regulating gene expression. When the host is invaded by the influenza virus, gene expression is regulated via changes in DNA methylation levels or patterns, leading to the activation or suppression of relevant signaling pathways or networks, triggering a series of immune responses against viral invasion. Here, we investigated the changes in genomic DNA methylation in the immune organs of chicken infected with H5N1 influenza virus.

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