Drosophila

Expression of Pink1 with α-synuclein in the dopaminergic neurons of Drosophila leads to increases in both lifespan and healthspan

A. M. Todd and Staveley, B. E., Expression of Pink1 with α-synuclein in the dopaminergic neurons of Drosophila leads to increases in both lifespan and healthspan, vol. 11, pp. 1497-1502, 2012.

Overexpression of the gene coding for α-synuclein has been shown to be an inherited cause of Parkinson disease. Our laboratory has previously co-expressed the parkin and Pink1 genes to rescue α-synuclein-induced phenotypes within a Drosophila model. To further investigate the effect of Pink1 in this model, we performed longevity and behavioral studies using several drivers to express the α-synuclein and Pink1 genes.

A broad expression profile of the GMR-GAL4 driver in Drosophila melanogaster

W. - Z. Li, Li, S. - L., Zheng, H. Y., Zhang, S. - P., and Xue, L., A broad expression profile of the GMR-GAL4 driver in Drosophila melanogaster, vol. 11, pp. 1997-2002, 2012.

The GAL4/UAS binary system has been widely used in Drosophila melanogaster for ectopic expression of transgenes in a tissue-specific manner. The GMR-GAL4 driver, which expresses the yeast transcription factor GAL4 under the control of glass multiple reporter (GMR) promoter elements, has been commonly utilized to express target transgenes, specifically in the developing eye.

Programmed cell death in salivary glands of Drosophila arizonae and Drosophila mulleri

P. Ianella, Azeredo-Oliveira, M. T. V., and Itoyama, M. M., Programmed cell death in salivary glands of Drosophila arizonae and Drosophila mulleri, vol. 7, pp. 476-486, 2008.

Programmed cell death (PCD) in insect metamorphosis assumes a great diversity of morphology and controlling processes that are still not well understood. With the objective of obtaining information about the PCD process, salivary glands of Drosophila arizonae and D. mulleri were studied during larval-pupal development. From the results, it can be concluded that the type of the PCD that occurs in these organs is morphologically typical of apoptosis (formation of apoptotic nuclei, followed by fragmentation into apoptotic bodies).

New evidence for nucleolar dominance in hybrids of Drosophila arizonae and Drosophila mulleri

C. I. Oliveira, Itoyama, M. M., and Bicudo, H. E. M. C., New evidence for nucleolar dominance in hybrids of Drosophila arizonae and Drosophila mulleri, vol. 5, pp. 632-637, 2006.

Drosophila mulleri (MU) and D. arizonae (AR) are cryptic species of the mulleri complex, mulleri subgroup, repleta group. Earlier cytogenetic studies revealed that these species have different regulatory mechanisms of nucleolar organizing activity. In these species, nucleolar organizing regions are found in both the X chromosome and the microchromosome. In the salivary glands of hybrids between MU females and AR males, there is an interspecific dominance of the regulatory system of the D.

Female remating, sperm competition and sexual selection in Drosophila

S. Ram Singh, Singh, B. N., and Hoenigsberg, H. F., Female remating, sperm competition and sexual selection in Drosophila, vol. 1. pp. 178-215, 2002.

Female remating is fundamental to evolutionary biology as it determines the pattern of sexual selection and sexual conflict. Remating in females is an important component of Drosophila mating systems because it affects sperm usage patterns and sexual selection. Remating is common in females of many species of Drosophila in both natural and laboratory populations. It has been reported in many insect species and also in vertebrates.

Subscribe to Drosophila