Drug-induced liver injury

CYP1A2 polymorphism in Chinese patients with acute liver injury induced by Polygonum multiflorum

K. F. Ma, Zhang, X. G., and Jia, H. Y., CYP1A2 polymorphism in Chinese patients with acute liver injury induced by Polygonum multiflorum, vol. 13, pp. 5637-5643, 2014.

The objective of this study was to evaluate the genotype and allelic frequencies of CYP1A2 in Chinese patients with acute liver injury induced by Polygonum multiflorum. We examined the clinical mechanism of acute liver injury induced by P. multiflorum. According to the diagnostic criteria for drug-induced liver injury (DILI), 43 cases of P. multiflorum-induced liver injury admitted to the First Affiliated Hospital, Zhejiang University were identified between January 2008 and December 2012.

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