End-stage renal disease

Association of vitamin D receptor gene polymorphisms with end-stage renal disease and the development of high-turnover renal osteodystrophy in a Chinese population

L. Y. Wang, Zhang, P., Wang, H. F., Qin, Z. W., Wei, K. B., Lv, X. A., Wang, L. Y., Zhang, P., Wang, H. F., Qin, Z. W., Wei, K. B., and Lv, X. A., Association of vitamin D receptor gene polymorphisms with end-stage renal disease and the development of high-turnover renal osteodystrophy in a Chinese population, vol. 15, p. -, 2016.

Two single nucleotide polymorphisms (SNPs; TaqI and ApaI) in the vitamin D receptor (VDR) gene have been identified as risk factors for the progression of end-stage renal disease (ESRD). The purpose of our study was to confirm the reported association of these two SNPs with ESRD risk and progression of renal osteodystrophy in a Chinese Han population. A total of 452 ESRD patients and 904 matched-pair controls (based on age, gender, and body mass index) were included.

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